Abstract: Introduction: The natural history of ocular manifestations is very poor in Behcet's Disease (BD). The lesions progress by successive attacks leading to sever loss of vision or blindness. Aggressive treatments, by the association of cytotoxic drugs and steroids, have dramatically changed the outcome. However, still some ophthalmologists are convinced that the improvement is temporary and in the long run the eyes progress toward blindness. The aim of this study was ...
Abstract: Introduction: The ocular lesions of Behcet's disease (BD) progress usually toward severe loss of vision or blindness, and therefore need aggressive treatment. However, even such a treatment is not always successful. We used classification and regression tree (cart) method to see if some factors could predict the result of the future treatment. Methods: Eight hundreds and thirty patients who fulfilled the Iran criteria for BD were selected for this study. They ...
Abstract: Purpose: Polymyositis (PM) is an inflammatory muscle disease, which has more overlap with scleroderma than other connective tissue diseases. The aim of this study is to compare the clinical, paraclinical and therapeutic response of polymyositis with polymyositis-scleroderma overlap syndrome. Methods: During the past 10 years we had 16 overlap syndromes and 40 primary polymyositis. All patients were classified by the American college of Rheumatology classification criteria. Ninety-seven items were checked in ...
Abstract: Introduction: The association of Behcet’s disease (BD) and Ankylosing Spondylitis (AS) is still a controversial subject. As the presence of sacroiliac joint (SIJ) involvement is an essential criterion in the diagnosis of AS, we decided to determine the prevalence of SIJ involvement in BD and compare it with control group. Materials & Methods: We selected randomly 199 BD patients and 168 non-BD cases (CG), in a 12 month period (between April ...
Abstract: Objective: Systemic sclerosis is a generalized disorder of connective tissue disease. This study surveyed the clinical manifestations of systemic sclerosis in early (6 years) phases of limited and diffuse variants. Methods: Nineteen patients with diffuse and thirty-four cases with limited form of disease were selected consecutively from 1992 to 1998. Sixty-five clinical data were evaluated and then analyzed by MC-Nemar chi square test between two forms in both phases. Results: (1) There were ...
Abstract: The neuropsychiatric manifestations of systemic lupus erythematosus are frequent. One of the most serious presentations is convulsion. This study was carried out to evaluate the relation between convulsion and anti-DNA antibody levels. An analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic SLE lupus erythematosus in Lupus Unit, Rheumatology Center, Shariati Hospital, Tehran University of Medical Sciences. The frequency Of convulsion was 13.3%. There ...
Abstract: Objective: Exercises, especially sports have an effective role in increasing of Bone Mineral Density (BMD). This study surveyed the bone density in athlete women compared to Iranian standard BMD at the same age and sex. Methods: This study was a prospective survey on thirty-nine athlete women between 20 to 30 years old. Subjects were selected randomly in six different athletes groups including basketball, volleyball, tennis, badminton, swimming and running. BMD was measured ...
Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ...
Abstract: The bone mass density (BMD) may vary in different countries due to different genetic and environmental factors. This study was performed to determine the BMD of the normal population in Iran. Subjects were selected randomly from different social workers classes in Tehran (from the lowest to the highest). For each decade and sexes, 20 normal subjects were selected (140 men and 140 women). BMD was measured with a Hologic 1000 ...
Abstract: Introduction: Behcet’s disease (BD) is not rare in children. Its clinical picture differs from adults. The purpose of this study was 1-To find the characteristics of juvenile BD (JBD). 2-To compare JBD with the adult from (ABD) of the disease. Materials & Methods: In a cohort of 3729 patients with BD, different manifestations of the disease, including 100 clinical and paraclinical data, were analyzed. Patients were divided in two groups. 1- ...